Struggling with Treatment-Resistant Depression? A New Option Might Be Available

If you've been battling depression and haven't found relief with traditional medications, you're not alone. Up to one-third of people with depression experience treatment-resistant depression (TRD), meaning multiple medications haven't brought significant improvement. But there's good news: a breakthrough treatment: Ketamine Therapy offers hope.


What is Ketamine Therapy?


Ketamine is a medication used as an anesthetic since 1962, and has been proven effective for psychiatric disorders. It can offer patients who are battling depression, anxiety and mood disorders a safe and proven therapy when other methods have failed. Unlike traditional antidepressants that work on serotonin levels, Ketamine works differently, potentially impacting brain circuits involved in mood regulation. Research suggests that Ketamine promotes the growth of new synapses in the prefrontal cortex resulting in greater connectivity in the brain.



T
hings to Consider About Ketamine


Insurance Coverage:
Ketamine isn't covered by insurance, though your office visit portion may be covered. Patient is responsible for the costs of supplies. We'll assess your coverage and provide you with a cost estimate


Clinic Visits
: Ketamine requires in-clinic administration due to potential side effects. You'll likely need to stay for monitoring for at least 

two hours and you cannot drive on days of treatment.


Side Effects:
Ketamine can cause dissociation (feeling disconnected from your body or surroundings), dizziness, and nausea. Talk to a healthcare professional about potential side effects and how to manage them.


Length of treatment:
Treatments usually involve one to two infusions per week for three to five weeks. Your provider will monitor your progress for long lasting results and may suggest additional maintenance treatments. 


Is it Right for You?


Ketamine offers a promising option for TRD, but it's important to weigh the pros and cons. Discuss it with your doctor or a mental health professional to see if it aligns with your needs and situation. They can help you understand the potential benefits and risks and determine if it is a good fit for your treatment plan.


Remember, you're not alone in this fight. There is help available, and new options are emerging. Talk to Blue Umbrella Psychiatry and explore all possibilities for managing your depression.

Child eating a snack indoors, with a thoughtful expression and blurred home background
October 29, 2026
Learn how to help anxious children navigate Halloween fears, sensory overload, and scary situations with supportive strategies that build comfort and confidence.
Hand reaching toward a row of colorful pencils on a white table
October 22, 2026
Learn what OCD really is, how obsessions and compulsions impact daily life, common symptoms to recognize, and when seeking mental health support may help today.
Patient seated on couch, covering face, while clinician in white coat offers support in a counseling session
October 15, 2026
Discover why mental health care is essential, how it impacts daily life, and why seeking support early can help improve overall wellbeing and quality of life.
Person slumped over a desk in a bright office, surrounded by laptop, papers, and plants
October 8, 2026
Learn the differences between stress, burnout, and depression, recognize common symptoms, and understand when mental health support may help you find relief.
Stressed coworkers at a desk, one holding her head, with headline about Sunday anxiety and workplace worries
October 1, 2026
Understand the Sunday Scaries, what causes workweek anxiety, how it affects your sleep and daily life, and when professional mental health support may help.
Hooded person sits on the floor with head in hands as black scribbles burst from the wall nearby
September 24, 2026
Learn how negative self-talk affects emotional wellness and discover ways to develop healthier thought patterns, build self-compassion, and improve mental health.
Crowded group of people in white shirts looking down at smartphones indoors
September 17, 2026
Learn how social media affects mental health, from anxiety and comparison to loneliness, and discover ways to create healthier online habits and digital boundaries.
Woman sitting apart and looking down while a group chats on a couch in the background
September 10, 2026
Learn how social isolation affects mental health, including loneliness, anxiety, and depression, and discover ways to rebuild meaningful connections and support.
Person sitting on outdoor steps, knees hugged to chest, head resting on arms, in warm sunlight.
September 3, 2026
Discover how anxiety affects the body, why physical symptoms occur, and how understanding the mind-body connection can help you manage stress and improve wellbeing.
Blue line drawing of a head with a stethoscope examining the brain
August 27, 2026
Discover why consistency matters in mental health treatment and how regular care, healthy routines, and ongoing support can help improve long-term wellness.